24. Basic fibroblast growth factor expression in human ovarian follicles
نویسندگان
چکیده
منابع مشابه
Basic fibroblast growth factor expression in isolated small human ovarian follicles.
Basic fibroblast growth factor (bFGF) is involved in cell proliferation, differentiation, and angiogenesis. It has long been known that bFGF acts as a powerful mitogen for various mammalian granulosa cells in culture. To investigate the possible involvement of bFGF expression in follicle initiation and growth in vivo, we performed nested RT-PCR on ovarian cortical biopsies and quantitative PCR ...
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STUDY QUESTION What is the effect of basic fibroblast growth factor (bFGF) on the growth of individual early human follicles in a three-dimensional (3D) culture system in vitro? SUMMARY ANSWER The addition of 200 ng bFGF/ml improves human early follicle growth, survival and viability during growth in vitro. WHAT IS KNOWN ALREADY It has been demonstrated that bFGF enhances primordial follicl...
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ژورنال
عنوان ژورنال: Reproduction, Fertility and Development
سال: 2003
ISSN: 1031-3613
DOI: 10.1071/srb03ab24